Job Description

We are seeking a Research Assistant for a 2-year-regular position (renewable) to work within the Vaccine Process Development Department at the International Vaccine Institute in Seoul, Korea. (Duty station: Seoul, Korea)

Job Description

This job is responsible in assisting supervisor or designed scientist in the research and process development activities (upstream, downstream) of vaccine candidate intermediates, drug substances and drug products.

Key Roles & Responsibilities

1. Assist in the development of upstream processes (fermentation) for bacterial and mammalian culture

Conduct fermentation trial at various scale from shake flask to fermenter (0.5 to 10L) for antigen/intermediate production
Develop assays to monitor vaccine candidate expression in fermenter and other relevant in process controls and assay.
Assist in development of scale-up studies for the fermentation process

2. Assist in the development of downstream processes (purification and conjugation) for different vaccine candidates (Bacterial and Viral)

Assess various purification methods for target antigen to produce the antigen at acceptable purity and cost effectiveness.
Develop assays to monitor target antigens during purification.
Develop assays for release and characterization of purified bulks – proteins, inactivated virus, polysaccharides and conjugates.
Perform scale up studies of developed purification and conjugation processes.

3. Analytical metho development for vaccine candidates and its qualification.

4. Support lab management

Keep detail records in notebook; prepare reports and other documentation as required.
Regular review of achievement of results and methods used while working under close supervision.
Support the purchasing of equipment and supplies, well-stocked in order to ensure smooth running of the laboratory.
Operate and maintain laboratory equipment.